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Drinking Coffee Linked to Reduced Risk of Endometrial Cancer

Porcelain Cup and CoffeeMore good news for women with a coffee habit: New research published in the journal Cancer Epidemiology, Biomarkers & Prevention suggests that drinking three to four cups of coffee a day could reduce the risk of endometrial cancer by almost a fifth.

Endometrial cancer, or cancer of the lining of the uterus, is the most common cancer of the female reproductive organs in the United States , affecting 1 in 37 women in their lifetime. Approximately 54,870 women will receive endometrial cancer or uterine sarcomas diagnoses this year, and 10,170 will die from the diseases.

Although the exact causes of endometrial cancer remain unclear, hormonal imbalances, diabetes, obesity, and unhealthy diets are some important factors that increase the risk.

For the present study, researchers led by Melissa A. Merritt, PhD, of Imperial College London in the United Kingdom sought to investigate the ways in which dietary factors affect the risk of endometrial cancer.

Using data on more than 456,000 women from the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study and the Nurses’ Health Study (NHS) or Nurses’ Health Study II (NHSII), the researchers evaluated the dietary habits of more than 2,800 women diagnosed with endometrial cancer. The women participating in the studies completed dietary questionnaires.

The researchers assessed the link between 84 foods and nutrients and the risk of endometrial cancer, ultimately identifying nine foods and nutrients that could be associated with risk of endometrial cancer: total fat, monounsaturated fat, phosphorus, carbohydrates, yogurt, butter, potatoes, cheese, and coffee.


According to the research, drinking three cups of coffee a day reduced the risk of endometrial cancer by 19 percent among women in the EPIC study compared to women who drank less than one cup of coffee a day. Drinking four cups of coffee a day reduced the risk of endometrial cancer by 18 percent among women in the NHS/NHSII study compared to women who never drank coffee.

In other words, drinking coffee appears to reduce the risk of endometrial cancer. People can utilize this benefit by having a calculated amount of coffee every day. They can, for instance, explore home coffee appliances such as jura machines to get a quick brew without having to spend a lot of time making a cup of coffee.

However, coffee in excess can cause neurological havoc, so it would be beneficial to maintain limited caffeine consumption instead of overdoing it.


Comments Merritt:

“We were not surprised by the results that a high versus low intake of coffee was associated with a reduced risk for endometrial cancer, because they were consistent with what has been observed in previous studies.

“We used similar methods to investigate the association between coffee intake and endometrial cancer as previous studies. This is important so we can compare results across different studies.”


“Coffee intake is worth investigating further to see if coffee can be used for the prevention of endometrial cancer.

“However, before clinical recommendations can be made, further studies are needed to evaluate this question in other studies and to try to isolate the components of coffee that may be responsible for any influence on endometrial cancer.”

The findings of the present study validate other research that shows coffee provides a beneficial effect in decreasing endometrial cancer. However, additional research is still necessary to confirm the link.

Another recent study found that drinking coffee could reduce the risk of melanoma skin cancer by 20 percent.


Coffee Linked to Possible Lower Endometrial Cancer Risk:
Investigation of Dietary Factors and Endometrial Cancer Risk Using a Nutrient-wide Association Study Approach in the EPIC and Nurses’ Health Study (NHS) and NHSII:
Study Links Coffee Intake with Reduced Risk of Endometrial Cancer:

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